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Histoplasmosis is a disease caused when airborne spores of the fungus Histoplasma capsulatum are inhaled in the lungs. Histoplasmosis is sometimes so mild that it produces no apparent symptoms. However, later it can lead to a serious eye disease called ocular histoplasmosis syndrome (OHS), a leading cause of vision loss in Americans ages 20 to 40.

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Histoplasmosis

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NEI Website Header Description: Confocal image of rat RPE layer two weeks after laser. A well-defined neovascular membrane labeled with Isolectin Ib4 (red) is detected below proliferating RPE cells (Phalloidin in green). New vessels are growing toward the subretinal space.